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Tranexamic Acid (TXA) has been safely utilized in both trauma and surgical settings to reduce blood loss. Peri-operative blood loss in the context of breast surgery may lead to patient discomfort, a prolonged hospital stay, additional procedures, skin necrosis, and loss of free tissue transfer flaps. Chloe Wong (@chloerw) and her co-authors from the McMaster University Division of Plastic and Reconstructive Surgery evaluated the effect of TXA on post-operative blood loss in breast surgery through a systematic review and meta-analysis. She and her co-authors found the use of TXA in breast surgery to be safe and effective, with a reduction in hematoma rates and no effect on seroma rates, postoperative drain output, or infection rates.?? The Effects of Tranexamic Acid in Breast Surgery: A Systematic Review and Meta-Analysis Minh NQ Huynh, MD1(@minhhu101); Chloe R. Wong, BHSc2 (@chloerw); Matthew C McRae, MD, MHS, FRCS(C)1; Sophocles Voineskos MD, MSc, FRCS(C)1; Mark H McRae, MD, MScCH, FRCS(C)1 1. Division of Plastic Surgery, McMaster University, Hamilton, Canada 2. Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Canada

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