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While the incidence of infection following autologous cranioplasty after decompressive craniectomy is well-documented, risk factors of infection remain contentious. Carole Spake @carole.spake and her co-authors from the Brown University Division of Plastic Surgery evaluated a retrospective database of 126 patients at their institution to identify possible risk factors for infection. The authors identified that subgaleal drain placement, regardless of defect size or length of use, provided a protective effect against infection. These findings suggest that subgaleal drains should be considered in all patients undergoing autologous cranioplasty regardless of defect size in order to help reduce the risk of infection.

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