Plastic Surgery Research Council
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PSRC 60th Annual Meeting
Program and Abstracts

PSRC 60th Annual Meeting
May 14 - 16, 2015
The Westin Seattle, Seattle, Washington

Preliminary Program   |   Posters

Thursday, May 14, 2015

7:00 am - 6:00 pm Registration
Cascade Ballroom Foyer
7:00 am - 6:00 pm Poster Set-Up
Puget Sound
7:00 - 8:00 am Continental Breakfast
Cascade Ballroom Foyer
8:00 am - 12:00 pm Local Programming
University of Washington, Harborview Medical Center
8:00 AM – 8:10 AM Local Program Introduction
David Mathes, MD
8:15 AM – 8:45 AM University of Washington Plastic Surgery
Nicholas Vedder, MD
8:45 AM – 9:30 AM Global Health 1995 to 2025 – Thirty Years in Thirty Minutes
David Shoultz, PhD, MBA
9:30 AM – 10:30 AM Washington Wine
Sandra Lee & Wine Maker
10:30 AM – 11:30 AM Generational Issues in Education
Anna Liotta
11:30 AM – 12:00 PM Transplantation Tolerance
Ranier Storb
12:00 - 12:15 pm Members Photograph
University of Washington, Harborview Medical Center
12:00 - 6:00 pm Speaker Ready Room
Cascade Ballroom Foyer
12:30 - 2:00 pm Lunch; Non-Members
Pine
12:30 - 2:00 pm Lunch & Business Meeting; Members only
Pike
1:45 - 6:00 pm Exhibits
Cascade Ballroom Foyer
2:00 - 3:00 pm Guest Speaker
Cascade Ballroom

Wound Healing: From Bench to Bedside and Back to Bench
Michael T. Longaker, MD
3:00 - 4:30 pm Session 1 Best Papers
Cascade Ballroom
Moderators: David Mathes, MD & Babak J. Mehrara, MD
3:00 pm 1. N-Acetylcysteine Improves Autologous Fat Graft Survival in a Mouse Model
Joshua A. Gillis, MD; Simon Gebremeskel, BSc; Kyle D. Phipps, PhD; Lori A. MacNeil, PhD; Christopher J. Sinal, PhD; Brent Johnston, PhD; Paul Hong, MD; Michael Bezuhly, MD
Dalhousie University, Halifax, NS, Canada
3:09 pm 2. Clinical Outcomes after a Modified End-to-Side Nerve Transfer Using the Phrenic Nerve as a Donor for Treatment of Brachial Plexus Injury
Jacques A. Machol, IV, MD1; Ji-Geng Yan, MD, PhD1; Robert Robert Fang, MD2; Lin-Ling Zhang, MD1; James Sanger, MD1; Hani Matloub, MD1
1Medical College of Wisconsin, Milwaukee, WI, 2Emory University, Atlanta, GA
3:18 pm 3. Regenerative Peripheral Nerve Interfaces: Impact of Decellularized Small Intestinal Submucosa on Regeneration, Reinnervation, and Revascularization
Frances M. Walocko, MSE; Elizabeth A. Mays, BSE; Zachary P. French, HS; Cheryl A. Hassett, BS; Jana D. Moon, BS; Nicholas B. Langhals, PhD; Paul S. Cederna, MD; Melanie G. Urbanchek, PhD
University of Michigan, Ann Arbor, MI
3:27 pm 4. Mammary Adipose Derived Stem Cells in BRCA-Related Breast Cancers
Irene J. Pien, BS1; Jared A. Blau, BS, MEd1; Michelle L. Bowie, MS2; Siya Lem, BS2; Victoria L. Seewaldt, MD2; Scott T. Hollenbeck, MD3
1Duke University School of Medicine, Durham, NC, 2Duke University Department of Medicine, Division of Medical Oncology, Durham, NC, 3Duke University Department of Surgery, Division of Plastic, Maxillofacial, and Oral Surgery, Durham, NC
3:36 pm 5. The Suture Provides a Niche for Mesenchymal Stem Cells of Craniofacial Bones
Hu Zhao, DDS, PhD; Jifan Feng, DDS, PhD; Mark Urata, DDS, MD; Yang Chai, DDS, PhD
University of Southern California, Los Angeles, CA
3:45 pm 6. Missense Variant in MAPK Inactivator PTPN5 is Associated with Decreased Severity of Post-Burn Hypertrophic Scarring
Ravi F. Sood, MD; Anne M. Hocking, PhD; Lara A. Muffley, BS; Maricar Ga, BS; Shari Honari, RN, BSN; Reiner P. Alexander, MD, MSc; Nicole S. Gibran, MD
UW Medicine Regional Burn Center, Seattle, WA
3:54 pm 7. Predicting Venous Congestion Before DIEP Breast Reconstruction
Christopher R. Davis, BSc, MB ChB, MRCS1; Lyn Jones, FRCS, FRCR2; Rachel Tillett, MSc, FRCS (Plast)3; Helen Richards, MRCS2, Sherif Wilson, FRCS (Plast)2
1Stanford University, Stanford University, CA, 2Southmead Hospital, Bristol, United Kingdom, 3Royal Devon and Exeter NHS Trust, Exeter, United Kingdom
4:03 pm 8. Understanding the Recovery Phase of Breast Reconstruction: Patient Reported Outcomes Correlated to Type and Timing of Reconstruction
Katie Weichman, MD1; Jennifer B. Hamill, MPH2; Hyungjin Myra Kim, ScD2; Xiaoxue Chen, BS2; Edwin G. Wilkins, MD, MS2; Andrea L. Pusic, MD, MHS3
1Montefiore Medical Center/Albert Einstein School of Medicine, Bronx, NY, 2University of Michigan, Ann Arbor, MI, 3Memorial Sloan Kettering Cancer Center, New York, NY
4:12 pm 9. Pullulan-Collagen Hydrogels Seeded with Adipose-Derived Mesenchymal Stem Cells Enhance Progenitor Cell Recruitment and Functionality
Janos Barrera, BS; Revanth Kosaraju, BS Candidate; Robert C. Rennert, MD; Zeshaan N. Maan, MBBS, MRCS; Dominik Duscher, MD; Alexander J. Whittam, BA; Melanie Rodrigues, PhD; Michael Januszyk, MD; Jayakumar Rajadas, PhD; Geoffrey C. Gurtner, MD, FACS
Stanford University, Stanford, CA
4:21 pm 10. The Role of Skin-Specific Immunobiology and Major Histocompatibility Complex Sharing in Vascularized Composite Allograft Tolerance
David A. Leonard, MBChB; Kumaran Shanmugarajah, MBBS; Harrison Powell, BS; Alexander Albritton, BS; Christopher Mallard, BS; David H. Sachs, MD; Curtis L. Cetrulo, Jr., MD; Josef M. Kurtz, PhD
Massachusetts General Hospital, Boston, MA
4:30 - 6:00 pm Session 2 Best Papers
Cascade Ballroom
Moderators: Paul S. Cederna, MD & Peter J. Taub, MD
4:30 pm 11. Cell-based Muscle Regeneration by utilizing Epigenetic Drug and Hydrogel
ShihJye Tan, MS, Zhi Yang, MD; Josephine Fang, MS; Yichen Wu, MS; Marcel Nimni, PhD; Mark Urata, MD, DDS; Bo Han, PhD
USC, Los Angeles, CA
4:39 pm 12. Ex Vivo Free Flap Transfection with Minicircle DNA for Targeted Localized Gene Therapy
Peter A. Than, MD; Robert R. Rennert, MD; Christopher R. Davis, BSc MB, ChB, MRCS; Shane Morrison, MD; Tai Le, Michael W. Findlay, MBBS, PhD, FRACS, FACS; Geoffrey C. Gurtner, MD, FACS
Stanford University School of Medicine, Stanford, CA
4:48 pm 13. Is there a Safe Lipoaspirate Volume? A Risk Assessment Model of Liposuction Volume as a Function of Body Mass Index Based on TOPS Data
Ian Chow, BA1; Mohammed S. Alghoul, MD1; Nima Khavanin, BS1; Philip J. Hanwright, BA1; Kristen E. Mayer, BS1; Keith M. Hume, MA3; Robert X Murphy Jr., MD, MA4; Karol A. Gutowski, MD2; John YS Kim, MD1
1Northwestern University, Chicago, IL, 2University of Illinois, Chicago, IL, 3American Society of Plastic Surgery, Chicago, IL, 4Lehigh Valley Health Network, Allentown, PA
4:57 pm 14. Is More Better? The Number of Lymph Nodes in the Vascularized Lymph Node Transfer Influences its Lymphaticovenous Drainage
Grzegorz Kwiecien, MD; Bahar Bassiri Gharb, MD, PhD; Kashyap Tadisina, BA; Maria Madajka, PhD; James E. Zins, MD; Graham S. Schwarz, MD
Cleveland Clinic, Cleveland, OH
5:06 pm 15. Dermal-Based Peripheral Nerve Interface for Transduction of Sensory Feedback from Upper Extremity Prostheses
Ian C. Sando, MD1; Gregory J. Gerling, PhD2; Daniel C. Ursu, MS1; Kristoffer B. Sugg, MD1; Yaxi Hu, BS1; Steven C. Haase, MD1; Nicholas B. Langhals, PhD1; Paul S. Cederna, MD1; Melanie G. Urbanchek, PhD1
1University of Michigan, Ann Arbor, MI, 2University of Virginia, Charlottesville, VA
5:15 pm 16. Adjacent Antagonistic RPNIs Produce Independent Signaling for Prosthesis Control
Andrej Nedic, MSE; Daniel Ursu, MS; Ian Sando, MD; Jana Moon, BS; Cheryl Hassett, BS; R Brent Gillespie, PhD; Nick Langhals, PhD; Paul Cederna, MD; Melanie Urbanchek, PhD
University of Michigan, Ann Arbor, MI
5:24 pm 17. In utero Transplantation of Gene Modified Human Adipose Stem Cells for Sustained Factor VIII Transgene Expression
Maricel G. Miguelino, MD; Christopher D. Pivetti, MS; David E. Sahar, MD; Jerry S. Powell, MD
University of California, Davis, Sacramento, CA
5:33 pm 18. Post Transplantation Cyclophosphamide Promotes Robust Immune Tolerance after Reconstructive Transplantation
Georg J. Furtmüller, MD; Madeline L. Fryer, BA; Byoungchol Oh, DVM; PhD; Sudipto Ganguly, PD; Jessica Izzi, DVM; Jeffrey Dodd-o, MD, PhD; Giorgio Raimondi, PhD; Damon S. Cooney, MD, PhD; WP Andrew Lee, MD, Leo Luznik, MD; Gerald Brandacher, MD
Johns Hopkins University, Baltimore, MD
5:42 pm 19. SDF-1 Mediates Pre-adipocyte Neovascular Potential and Slows Progression of Type 2 Diabetes
Janos Barrera, BS; Zeshaan Maan, MBBS, MSc, MRCS; Alexander J. Whittam, BA; Robert Rennert, MD; Dominik Duscher, MD; Kevin Paik, BA; Michael Hu, MD, MS, MPH; Graham Walmsley, BA; Michael T. Longaker, MD, MBA; Geoffrey C. Gurtner, MD, FACS
Stanford School of Medicine, Palo Alto, CA
5:51 pm 20. Defining the Role of the Vasculogenic Niche in Trauma-induced Heterotopic Ossification using Novel Imaging and Lineage-tracing Mice
Shailesh Agarwal, MD1; Shawn Loder, BS1; Cameron Brownley, BS1; Jonathan Peterson, BS1; Eboda Oluwatobi, BS1; Ronald Tompkins, MD2; David Herndon, MD3; Hsiao Sung, DDs, MD1; Wenzhao Zeng, PhD4; Dolrudee Jumlongras, PhD5; Bjorn Olsen, PhD5; Paul S. Cederna, MD1; Steven R. Buchman, MD1; Benjamin Levi, MD1
1University of Michigan, Ann Arbor, MI, 2Massachusetts General Hospital, Boston, MA, 3University of Texas Medical Branch, Galveston, TX, 4Stanford University, Stanford, CA, 5Harvard Dental School, Boston, MA
7:00 - 10:00 pm Welcome Reception
The Space Needle
 

Friday, May 15, 2015

7:00 am - 5:30 pm Registration
Cascade Ballroom Foyer
7:00 am - 5:30 pm Speaker Ready Room
Cascade Ballroom Foyer
7:00 am - 5:30 pm Exhibits
Cascade Ballroom Foyer
7:00 - 8:00 am Continental Breakfast with Exhibitors
Cascade Ballroom Foyer
8:00 - 9:30 am Session 3 Best Papers
Cascade Ballroom I
Moderators: Gregory H. Borschel, MD, FAAP, FACS & Christine H. Rohde, MD
8:00 am 21. Therapeutic Modulation of an Embryonic Fibroblast Lineage
Graham G. Walmsley, BA; Michael S. Hu, MD; Zeshaan N. Maan, MD; Yuval Rinkevich, PhD; Michael Januszyk, MD; Dominic Duscher, MD; Alexander Whittam, BA; David Atashroo, MD; Ruth Tevlin, MD; Elizabeth Zielins, MD; Peter H. Lorenz, MD; Irving L. Weissman, MD; Geoffrey C. Gurtner, MD; Michael T. Longaker, MD
Stanford University, Stanford, CA
8:09 am 22. Cd4+ Cells Home to and Initiate Pathological Changes of Lymphedema after Lymphatic Injury
Gabriela D. Garcia Nores, MD1; Daniel A. Cuzzone, MD2; Jason C. Gardenier, MD1; Ira L. Savetsky, MD1; Jeremy S. Torrisi, BA1; Matthew D. Nitti, BA1; Geoffrey E. Hespe, BS1; Raghu P. Kataru, PhD1; Babak J. Mehrara, MD1
1Memorial Sloan Kettering Cancer Center, New York, NY, 2New York University Hospital Center, New York, NY
23. WITHDRAWN
8:18 am 24. Effects of Obesity and Diabetes Mellitus on Adipose Tissue Derived Stromal Cells- Implications for Health, Massive Weight Loss and Therapeutics
Michael W. Findlay, MBBS, PhD, FRACS, FACS; Robert C. Rennert, MD; Michael Sorkin, MD; Michael Januszyk, MD; Peter A. Than, MD; Christopher Davis, MBBCh, MRCS; H. Peter Lorenz, MD, FACS; Homero Rivas, MD, MBA, FACS; John M. Morton, MD, FACS; Geoffrey C. Gurtner, MD, FACS
Stanford University, Stanford, CA
8:27 am 25. Enhancement of Nerve Regeneration after Delayed Repair with Controlled Release of Neurotrophic Factors
Kasra Tajdaran, MASc1; M. Cecilia Alvarez-Veronesi, MASc1; Matthew D. Wood, PhD2; Molly S. Shoichet, PhD1; Tessa Gordon, PhD1; Gregory H. Borschel, MD, FACS, FAAP1
1University of Toronto, Toronto, ON, Canada, 2Washington University, St. Louis, MO
8:36 am 26. Added Risk in Patients Undergoing Matching Procedures at Time of Immediate Breast Reconstruction: An ACS-NSQIP Study of 24,191 Patients
Mohamad Sebai, MBBS; Carisa Cooney, MPH; Buchi Ogbuagu, MD, MPH; Pablo Baltodano, MD; Chris Devulapalli, MD; Michele Manahan, MD; Gedge Rosson, MD
Johns Hopkins Hospital, Baltimore, MD
8:45 am 27. Tissue-Engineered, Vascularized Skin Flaps Containing Dermal Appendages
Rachel C. Hooper, MD; Adam M. Jacoby, BA; Ope A. Asanbe, MD; Wilmina N. Landford, BA; Peipei Zhang, PhD; Hector L. Osoria, BS; Alice Harper, BA; Jason A. Spector, MD, FACS
Weill Cornell Medical College, New York, NY
8:54 am 28. Propranolol Alters IH Development Via Beta2-adrenergic Receptor Blockade
Ryan W. England, BS; Naikhoba C.O. Munabi, BA; Jan K. Kitajewski, PhD; Carrie J. Shawber, PhD; June K. Wu, MD
Columbia University, New York, NY
9:03 am 29. Endothelial CXCL12 Recruits a Novel Circulating Progenitor Cell in Response to Tissue Injury
Zeshaan N. Maan, MBBS, MSc, MRCS; Dominik Duscher, MD; Alexander J. Whittam, BA; I N. Vial, MD; Michael Januszyk, MD, PhD; Lauren Fischer, MD; Robert C. Rennert, MD; Melanie Rodrigues, PhD; Michael S. Hu, MD, MS, MPH; Graham G. Walmsley, BA; Michael T. Longaker, MD, MBA; Geoffrey C. Gurtner, MD, FACS
Stanford University School of Medicine, Stanford, CA
9:12 am 30. A Nonsurgical, Lifelong Animal Model Lymphedema through Toxin-mediated Lymphatic Ablation
Jason C. Gardenier, MD; Gina T. Farias-Eisner, MD; Raghu P. Kataru, PhD; Ira L. Savetsky, MD; Jeremy S. Torrisi, BA; Gabriela D. Garcia Nores, MD; Matthew D. Nitti, BA; Geoffrey E. Hespe, BS; Babak J. Mehrara, MD
Memorial Sloan Kettering Cancer Center, New York, NY
9:30 - 10:30 am Panel Debate Session
Cascade Ballroom

Department of Surgery vs. Department of Plastic Surgery
Department of Surgery Point: Michael W. Neumeister, MD
Department of Plastic Surgery: J. Peter Rubin, MD; W.P. Andrew Lee, MD, Gregory Evans, MD,
Paul Cederna, MD

10:30 - 11:00 am Coffee with Exhibitors
Cascade Ballroom Foyer
11:00 - 11:30 am Session 4 Best EPSRC Papers
Cascade Ballroom I
Moderators: David Mathes, MD & Lars Steinstraesser, MD, FACS
11:00 am 31. Malignant Melanoma Thickness and Risk of Future Malignancies
Katie Young, BSc, MBChB1, 2; Alexander Ives, BSc3; Tim Jones, BSc, PHD3; Julia Verne, BSc MBBS, MSc, PhD, FFPH3; Alex Varey, MBChB, PhD, MRCS2; Yoav Ben-Shlomo, MBBS, MSc, PhD, MRCP1
1University of Bristol, School of Social and Community Medicine, Bristol, United Kingdom, 2North Bristol NHS Trust, Department of Plastic Surgery, Bristol, United Kingdom, 3Public Health England South West, Bristol, United Kingdom
11:10 am 32. Impaired Regenerative Ability of Aged and Diabetic Adipose Derived Stem Cells is Caused by Depletion of Cell Subpopulations
Dominik Duscher, MD1; Robert. C. Rennert, MD1; Michael Januszyk, MD1; Zeshaan N. Maan, MD1; Alexander J. Whittam, BA1; Graham G. Walmsley, BA1,2; Michael S. Hu, MD1; Geoffrey C. Gurtner, MD1
1Stanford University, Division of Plastic Surgery, Stanford, CA, 2Stanford University, Institute for Stem Cell Biology and Regenerative Medicine, Stanford, CA
11:20 am 33. Reliability and Validity of RPNI Signaling of Gait Phases during Voluntary Walking
Andrej Nedic, MSE1; Daniel C. Ursu, MS2; Jana Moon, BS1; Cheryl Hassett, BS1; R. Brent Gillespie, PhD2; Nicholas B. Langhals, PhD1; Paul Cederna, MD1; Melanie Urbanchek, PhD1
1University of Michigan, Plastic and Reconstructive Surgery, Ann Arbor, MI, 2University of Michigan, Mechanical Engineering, Ann Arbor, MI
11:30 am 34. WITHDRAWN
11:30 am - 1:00 pm Lunch
Cascade Ballroom Foyer
1:00 - 2:30 pm Session 5 Group A
Cascade Ballroom I
Moderators: Duc T. Bui, MD; Shannon M. Colohan, MD & Otway Louie, MD
1:00 pm 35. The Use of Co2 Fractional Photothermolysis for the Treatment of Burn Scars
Benjamin Levi, MD; Amir Ibrahim, MD; Katie Mathews, BA; Brandon Wojcik, MD; Jason Gomez, BS; Shawn Fagan, MD, FACS; William Gerald Austen, Jr., MD, FACS; Jeremy Goverman, MD, FACS
Massachusetts General Hospital, Boston, MA
1:07 pm 36. Comparing the Sartorius versus the Rectus Femoris Flap in the Treatment of the Infected Vascular Graft Groin Wound: A Cost-Utility Analysis
Abhishek Chatterjee, MD, MBA1; Tomasz Kosowski, MD, MBA2; Bryan Pyfer, BS3; Julia Tchou, MD, PhD1; Carla Fisher, MD1; Sirish Maddali, MD4
1University of Pennsylvania, Philadelphia, PA, 2Miami Breast Center, Miami, FL, 3Dartmouth Medical School, Lebanon, NH, 4Plastic and Hand, Portland, ME
1:14 pm 37. A Qualitative Study of Breast Reconstruction Decision-making Among Asians
Michelle M. Chang, BS; Rose Fu, MD; Margaret Chen, MD; Christine Rohde, MD, MPH
New York Presbyterian Hospital/Cornell-Columbia, New York City, NY
1:21 pm 38. Short-term Adverse Outcome Comparison in Autologous Breast Reconstruction: Latissimus, Free, and TRam Flaps
Benjamin B. Massenburg, BA; Paymon Sanati-Mehrizy, BA; Michael J. Ingargiola, MD; Jonatan Hernandez Rosa, MD; Peter Taub, MD
Icahn School of Medicine at Mount Sinai, New York, NY
1:28 pm 39. A Qualitative Study of Breast Reconstruction Decision-Making Among Asians
Michelle M. Chang, BS; Rose Fu, MD; Margaret Chen, MD; Christine Rohde, MD, MPH
Columbia University Medical Center, New York, NY
1:35 pm 40. A Meta-Analysis Assessing Post-Surgical Outcomes between Aseptic and Sterile AlloDerm Regenerative Tissue Matrix
David Macarios, MBA1; Leah Griffin, MS2; Abhishek Chatterjee, MD; MBA3; Lauren J. Lee, PharmD, MS1; Cheryl Milburn, MS, MLIS1; Maurice Y. Nahabedian, MD4
1LifeCell an Acelity company, Bridgewater, NJ, 2Acelity, San Antonio, TX, 3University of Pennsylvania Hospital, Philadelphia, PA, 4Georgetown University Department of Plastic Surgery, Washington, DC
1:42 pm 41. Perioperative Anticoagulation Increases the Risk of Complications after Cranioplasty
Eric W. Sankey, BS1; Joseph Lopez, MD, MBA2; Shuting Zhong, BS3; Ignacio Jusue-Torres, MD2; Jason Liauw, MD2; Judy Huang, MD2; Henry Brem, MD2; Chad Gordon, DO2
1Johns Hopkins University School of Medicine, Baltimore, MD, 2Johns Hopkins Hospital, Baltimore, MD, 3University of Illinois College of Medicine, Rockford, IL
1:49 pm 42. Volumetric Changes of the Pedicled Tram Flap and the Contralateral Native Breast in the Long Term Follow Up
Eun Key Kim, MD, PhD; Jin Sup Eom, MD, PhD; Taik Jong Lee, MD; PhD, Hee Jong Lee, MD; Young Chul Seo, MD; Ji Young Yun, MD; Sang Shin Lee, MD
Asan Medical Center, Seoul, Korea, Republic of
1:56 pm 43. Risk Analysis for Post-Operative Complications after Immediate Tissue Expander Breast Reconstruction (TE-IBR)
Gabriel Klein, MD1; Bret T Phillips, MD, MBA2; Wilmena Landford, BS1; A. Laurie Shroyer, PhD1; Duc Bui, MD1; Alex Dagum, MD1; Sami Khan, MD1
1Stony Brook University Hospital, Stony Brook, NY, 2Duke University, Division of Plastic, Maxillofacial and Oral Surgery, Durham, NC
2:03 pm 44. Outcomes and Safety of Combined Abdominoplasty-Hysterectomy versus the Individual Procedures
Benjamin B. Massenburg, BA; Paymon Sanati-Mehrizy, BA; Michael J. Ingargiola, MD; Jonatan Hernandez Rosa, MD; Peter J. Taub, MD; FACS, FAAP
Icahn School of Medicine at Mount Sinai, New York, NY
2:10 pm 45. Maintenance of Certification: Do Current Practice Patterns in Craniomaxillofacial Surgery Follow Evidence-Based Medicine?
Michael S. Gart, MD1; Arun K. Gosain, MD2
1Northwestern University, Chicago, IL, 2Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL
2:17 pm 46. Body Image and Quality of Life: Changes with Gastric Bypass Surgery and Body Contouring
Nirav B. Patel, MD, MS, JD1; Sven Gunther, AS, BS2; Ping Song, BA3; Chin-Shang Li, PhD4; Nathan A. Kludt, MD5; Carolyn Y.G. Lee, RN, MSN, ANP-C, PSN1; Shannon M. Hearney, BS Candidate6; Kamlesh B. Patel, MD7; Mohamed R. Ali, MD8; Michael S. Wong, MD1
1UC Davis Medical Center, Division of Plastic Surgery, Sacramento, CA, 2UC Davis School of Medicine, Sacramento, CA, 3Virginia Commonwealth University School of Medicine, Richmond, VA, 4UC Davis School of Medicine, Division of Biostatistics, Sacramento, CA, 5Joseph R. Burlin, MD, Inc., Stockton, CA, 6University of California, Davis, Davis, CA, 7Washington University School of Medicine, St. Louis, MO, 8UC Davis Medical Center, Division of Bariatric Surgery, Sacramento, CA
1:00 - 2:30 pm Session 5 Group B
Cascade Ballroom II
Moderators: Anuja K. Antony, MD; Christopher Derderian, MD & Sami Khan, MD
1:00 pm 47. Outcomes of a Hand Surgery Mission to Honduras
Carolyn Chuang, BS1; Jacob Azurdia, MD2; David Asuzu, PhD1; Kyle Ragins, BA1; Grant Thomson, MD1
1Yale School of Medicine, New Haven, CT, 2University of Toledo College of Medicine and Life Sciences, Toledo, OH
1:07 pm 48. Characterization of Factors Leading to Heterotopic Ossification in Adult Burn Injury Using a Large Multi-Institutional Burn Database
Aviram M. Giladi, MD, MS1; Prakash Jayakumar, MBBS2; Lewis Kazis, SD3; Katie Mathews, BA4; Karen Kowalske, MD5; Dagmar Amtmann, PhD6; Jeffrey C. Schneider, MD7; Paul S. Cederna, MD1; Colleen M. Ryan, MD, FACS8; Benjamin Levi, MD1
1University of Michigan, Ann Arbor, MI, 2Massachusetts General Hospital, Boston, MA, 3Boston University, Boston, MA, 4Harvard University Medical School, Boston, MA, 5University of Texas Southwestern, Dallas, TX, 6University of Washington, Seattle, WA, 7Harvard University Medical School/Spaulding Rehabilitation Hospital, Boston, MA, 8Massachusetts General Hospital/Shriners Hospital for Children-Boston, Boston, MA
1:14 pm 49. PEMF Modulates Cytokines in the Wound Milieu to Reduce Post-Operative Inflammation: Application to Autologous Breast Reconstruction
Naikhoba C. O. Munabi, BA, June K. Wu, MD, Erin M. Taylor, MD, Jeffrey A. Ascherman, MD, Arthur A. Pilla, PhD, Christine H. Rohde, MD, MPH
Columbia University, New York, NY
1:21 pm 50. Optimizing Satisfaction with Care in Breast Reconstruction
Wess A. Cohen, MD1; Tiffany N.S. Ballard, MD2; Jennifer B. Hamill, MPH2; Hyungjin M. Kim, ScD3; Xiaoxue Chen, BS3; Stefan J. Cano, PhD4; Edwin G. Wilkins, MD, MS2; Andrea L. Pusic, MD, MHS1
1Memorial Sloan Kettering Cancer Center, New York, NY, 2University of Michigan Health System, Ann Arbor, MI, 3University of Michigan, Ann Arbor, MI, 4Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, United Kingdom
1:28 pm 51. Immediate versus Delayed Reconstruction after Mastectomy -- An Analysis of 30 Day Post-Operative Outcomes
Paymon Sanati-Mehrizy, BA; Benjamin B. Massenburg, BA; John M. Rozehnal, BA; Michael J. Ingargiola, MD; Jonatan Hernandez-Rosa, MD; Peter J. Taub, MD
Icahn School of Medicine at Mount Sinai, New York, NY
1:35 pm 52. Outcomes of Craniofacial Microsomia Treatment: Microtia Reconstruction
Rachel S. Mandelbaum, BA1; Deborah B. Martins, BS1; Sarah Park, BS1; Emily Dubina, MD1; Akira Ishiyama, MD2; James P. Bradley, MD1; Justine C. Lee, MD, PhD1
1UCLA Division of Plastic and Reconstructive Surgery, Los Angeles, CA, 2UCLA Department of Head and Neck Surgery, Los Angeles, CA
1:42 pm 53. Are Patients with Low Body Mass Index Candidates for Deep Inferior Epigastric Perforator Flaps for Unilateral Breast Reconstruction?
Pieter G. Koolen, MD; Neel A. Kantak, MD; Colette Martin, BS; Adam M. Tobias, MD; Bernard T. Lee, MD, MBA; Samuel J. Lin, MD
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
1:49 pm 54. Polysomnogram Parameters of Children with and without Robin Sequence Undergoing Cleft Surgery are Not Significantly Different
Justine M. McGauley, BA; Jeremy Goss, BA; Eric Adjei Boakye, MA; Margie S. Hunter, BS; Paula Buchanan, MPH, PhD; Shalini Paruthi, MD; Alexander Y. Lin, MD
Saint Louis University, St. Louis, MO
1:56 pm 55. Patients with Clefts Who Undergo Sleep Studies after Surgery do not Show Significantly Improved Sleep Parameters after Adenotonsillectomy
Justine M. McGauley, BA; Jeremy Goss, BA; Eric Adjei Boakye, MA; Margie S. Hunter, BS; Paula Buchanan, MPH, PhD; Shalini Paruthi, MD; Alexander Y. Lin, MD
Saint Louis University, St. Louis, MO
2:03 pm 56. Long Term Outcomes of Total Knee Arthroplasty Following Soft Tissue Defect Reconstruction with Flaps
Grzegorz Kwiecien, MD; Grigorios Lamaris, MD, PhD; Bahar Bassiri Gharb, MD, PhD; Trevor Murray, MD; Mark F. Hendrickson, MD; James E. Zins, MD; Raymond Isakov, MD
Cleveland Clinic, Cleveland, OH
2:10 pm 57. Does Time affect Patient Satisfaction?
Wess A. Cohen, MD, Nima P. Patel, MD
Maimonides Medical Center, Brooklyn, NY
2:17 pm 58. Patient Perceived Benefit in Facial Aesthetic Procedures: The FACE-Q as a Tool to Study Botulinum Toxin Injection Outcomes
Anthony J. Taglienti, MD1; Anthony Wilson, MD1; Brian Chang, BA2; Nancy Folsom, RN1; Catherine Chang, MD1; Bianca Chin, MD1; Ivona Percec, MD, PhD1
1Hospital of the University of Pennsylvania, Philadelphia, PA, 2Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
1:00 - 2:30 pm Session 5 Group C
Elliott Bay
Moderators: Clara Lee, MD, MP; Paul Y. Liu, MD & Deepak Narayan, MD
1:00 pm 59. Quantification of Operative Time and the Factors that Prolong Microsurgical Breast Free Flap Procedures
Nelson Rodriguez-Unda, MD; Jose M. Flores, MPH; Carisa M. Cooney, MPH; Gedge D. Rosson, MD
Johns Hopkins School of Medicine, Baltimore, MD
1:07pm 60. The Impact of Hormonal Therapy on Outcomes of Total Skin-Sparing Mastectomy and Immediate Tissue Expander-Based Breast Reconstruction
Frederick Wang, MD; Anne Warren Peled, MD; Barbara Fowble, MD; Michael Alvarado, MD; Cheryl Ewing, MD; Laura Esserman, MD, MBA; Robert Foster, MD; Hani Sbitany, MD
University of California, San Francisco, San Francisco, CA
1:14 pm 61. Effect Modifiers of Radiation Risks in Total Skin-Sparing Mastectomy with Immediate Tissue Expander-Implant Reconstruction
Frederick Wang, MD; Anne Warren Peled, MD; Barbara Fowble, MD; Michael Alvarado, MD; Cheryl Ewing, MD; Laura Esserman, MD, MBA; Robert Foster, MD; Hani Sbitany, MD
University of California, San Francisco, San Francisco, CA
1:21 pm 62. The Bipedicle-Conjoined Deep Inferior Epigastric Perforator Flap for Unilateral and Bilateral Breast Reconstruction: A Concept in Evolution
Pieter G. Koolen, MD1; Bernard T. Lee, MD, MBA1; Samuel J. Lin, MD1; Heather Erhard, MD2; David T. Greenspun, MD, MSc3
1Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 2Albert Einstein College of Medicine, Bronx, NY, 3Greenwich Hospital, Greenwich, CT
1:28 pm 63. A Quantitative Analysis of Different Botulinum Toxin Formulations: A Randomized Double Blind Prospective Clinical Trial of Comparative Dynamic Strain Reduction
Catherine S Chang MD, Anthony J. Wilson, MD; Brian Chang, BS; Bianca C. Chin, MD; Anthony J. Taglinenti, MD; Nancy Folsom, RN; Ivona Percec, MD, PhD
University of Pennsylvania, Philadelphia, PA
1:35 pm 64. Assessing Recurrence Rates Following Wide Local Excision of Head and Neck Malignant Melanoma: Immediate versus Delayed Reconstruction
Tiago R. Matos, MD MSc.2, Pieter G. Koolen, MD1, Ahmed M. S. Ibrahim, MD1, Jie Sun, BA3, Bernard T. Lee, MD, MBA1, Robert A. Frankenthaler, MD1, Samuel J. Lin, MD1
1Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 2Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 3Harvard School of Dental Medicine, Boston, MA
  65. WITHDRAWN
1:42 pm 66. Is Vicryl Mesh Really a Safe Alternative to Acellular Dermis in Tissue Expander-based Breast Reconstruction?
Stacy Henderson, MD; Brett Michelotti, MD; Susie Sun, MD; Cathy Henry, MD; Dino Ravnic, MD; T. Shane Johnson, MD; Donald Mackay, MD; John Potochny, MD
Penn State Milton S. Hershey Medical Center, Hershey, PA
1:49 pm 67. The Clinical Efficacy and Financial Impact of Laser-assisted Indocyanine Green Angiography on Implant-based Breast Reconstruction at a Large Academic Medical Center
Christin A. Harless, MD; Sue Visscher, PHD; Steven R. Jacobson, MD
Mayo Clinic, Rochester, Rochester, MN
1:56 pm 68. Comparative Study of Liposomal Bupivacaine versus Paravertebral Block for Pain Control Following Mastectomy with Immediate Tissue Expander Reconstruction
Jad M. Abdelsattar, MBBS; Judy C. Boughey, MD; Anita T. Mohan, MRCS; Aodhnait S. Fahy, BMBCh, PhD; Whitney J. Goede, PharmD; Prakriti Gaba, BS; Bill Tran, MD; W. Scott Harmsen, MS; Christopher J. Jankowski, MD; James W. Jakub, MD; Tina J. Hieken, MD; Amy C. Degnim, MD; David R. Farley, MD; Karim Bakri, MBBS; Steven R. Jacobson, MD; Valerie Lemaine, MD; Renata L. Maricevich, MD; Michel Saint-Cyr, MD
Mayo Clinic, Rochester, MN
2:03 pm 69. Intrathoracic Muscle Flaps: Comparison of Outcomes for Infection versus Prophylactic Airway Coverage
Ziyad S. Hammoudeh, MD; Amelia C. Van Handel, BS; Akhavan A. Arya, BS; Francis C. Nichols, III, MD; Brian T. Carlsen, MD; Steven L. Moran, MD
Mayo Clinic, Rochester, MN
2:10 pm 70. Immediate Implant Exchange During Acute Infection in the Setting of Breast Reconstruction
Russell E. Ettinger, MD; Shailesh Agarwal, MD; Theodore A. Kung, MD; David L. Brown, MD
University of Michigan, Ann Arbor, MI
2:17 pm 71. T-regulatory Cell Proliferation after Lymphatic Injury Regulates Immune Function in Lymphedema
Ira L. Savetsky, MD; Swapna Ghanta, MD; Nicholas J. Albano, BS; Jason C. Gardenier, MD; Jeremy S. Torrisi, BA; Gabriela D. Garcia Nores, MD; Matthew D. Nitti, BA; Geoffrey E. Hespe, BS; Raghu P. Kataru, PhD; Babak J. Mehrara, MD, FACS
Memorial Sloan Kettering Cancer Center, New York, NY
2:30 - 3:00 pm Coffee with Exhibitors
Cascade Ballroom Foyer
3:00 - 4:30 pm Session 6 Group A
Cascade Ballroom I
Moderators: Alexander Y. Lin, MD, FACS, Reza Jarrahy, MD & Justin M. Sacks, MD
3:00 pm 72. Endothelial Cells from Capillary Malformations are Enriched for Somatic GNAQ Mutations and Aberrantly Express PDGFR?
Javier A. Couto, BS; Lan Huang, PhD; Matthew P. Vivero, BA; Nolan Kamitaki, BA; Reid A. Maclellan, MD, MMSc; John B. Mulliken, MD; Joyce Bischoff, PhD; Matthew L. Warman, MD; Arin K. Greene, MDc; MMSc
Boston Children's Hospital, Harvard Medical School, Boston, MA
3:07 pm 73. A Somatic MAP3K3 Mutation is Associated with Verrucous Venous Malformation
Javier A. Couto, BS; Matthew P. Vivero, BA; Harry P.W. Kozakewich, MD; Amir H. Taghinia, MD; John B. Mulliken, MD; Matthew L. Warman, MD; Arin K. Greene, MD, MMSc
Boston Children's Hospital, Harvard Medical School, Boston, MA
3:14 pm 74. Palate and Mandibular Form are Regulated by Actin Capping Protein CAPZB Function
Kusumika Mukherjee, PhD1, Kana Ishii, MD1, Michael J. Grimaldi, B.A.1, Christina Nguyen, BS1, Michael Talkowski, PhD1, James Gusella, PhD1, Richard Maas, MD, PhD2, Cynthia C. Morton, PhD2, Eric C. Liao, MD, PhD1
1Massachusetts General Hospital, Boston, MA, 2Brigham and Women's Hospital, Boston, MA
3:21 pm 75. Identification of Mandibular Growth Center via Clonal Cell Analysis
Irving TC Ling, MBBS, MRCSEd; Lucie Rochard, PhD; Eric C. Liao, MD; PhD
Massachusetts General Hospital, Harvard Medical School, Boston, MA
3:28 pm 76. Hair Follicle Specific ALK2/ACVR1 Critically Regulates Stem Cell Maintenance and Skin Development
Michael Sorkin, MD; Shailesh Agarwal, MD; Shawn Loder, BS; Cameron Brownley, BS; Kavitha Ranganathan, MD; Jon Li, MD; Shuli Li, PhD; Paul Cederna, MD; Benjamin Levi, MD
University of Michigan, Ann Arbor, MI
3:35 pm 77. Modeling Pfeiffer Syndrome in Zebrafish by CRISPR-targeted Homologous Recombination
Joanna P. Tomaszewski, MS; Arun K. Gosain, MD; Jolanta M. Topczewska, PhD
Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL
3:42 pm 78. Generating an irf6 Mutant Model for Rapid Analysis of Human Genetic Variants, Elucidate Gene Regulatory Network, and Drug Discovery to Mitigate Cleft Lip and Palate
Christina A. Nguyen, BS; Edward B. Li, BA; Kusumika Mukherjee, PhD; Lisa Gfrerer, MD; Eric C. Liao, MD, PhD
Massachusetts General Hospital, Boston, MA
3:49 pm 79. Whole-Proteome Analysis of Craniosynostotic Tissue Suggests a Link Between Inflammatory Signaling and Premature Suture Fusion
Sarah Lyon, BS1; Michael Januszyk, MD2; Anoop Mayampurath, PhD1; Darrel J. Waggoner, MD1; David M. Frim, MD1; Tong-Chuan He, MD, PhD1; Russell R. Reid, MD PhD1
1University of Chicago, Chicago, IL, 2Stanford University, Stanford, CA
3:56 pm 80. TWIST1 Silencing Enhances in vitro and in vivo Osteogenic Differentiation of Human Adipose Derived Stem Cells by Triggering Activation of BMP-ERK/FGF Signaling and TAZ Upregulation
Kshemendra Senarath-Yapa, MA, MBBChir, MRCS1, Natalina Quarto, PhD1, Andrea Renda, PhD2, Michael Longaker, MD MBA1
1The Hagey Laboratory for Pediatric Regenerative Medicine, Stanford University, Stanford, CA, 2Dipartimento di Scienze Biomediche Avanzate, Universita’ degli Studi di Napoli, Napoli, Italy
4:03 pm 81. Impact of koliber Mutation on Patency of Cranial Suture in Zebrafish
Jolanta M. Topczewska, PhD; Rupa Mirmira, BS; Joanna P. Tomaszewski, MS; Rebecca Anderson, PhD candidate; Jacek Topczewski, PhD; Arun Gosain, MD
Northwestern Feinberg School of Medicine, Chicago, IL
4:10 pm 82. BMP-2 Use in Alveolar Cleft Repair is Associated with an Increased Incidence of Postoperative Nasal Stenosis
Jeremy A. Goss, BA; Margie S. Hunter, BS; Alexander Y. Lin, MD
Saint Louis University School of Medicine, St. Louis, MO
4:17 pm 83. Connective Tissue Growth Factor (CTGF/CCN2) is Essential for Secondary Palatogenesis
Alex G. Lambi, BA1; Joseph T. Tarr, BA1; David I. Hindin, MD2; Christina Mundy, PhD1; Honey Hendesi, PhD1; Steven N. Popoff, PhD1; James P. Bradley, MD2
1Temple University School of Medicine, Philadelphia, PA, 2Temple University Hospital, Philadelphia, PA
3:00 - 4:30 pm Session 6 Group B
Cascade Ballroom II
Moderators: Eric Chang, MD & Anand R. Kumar, MD
3:00 pm 84. Surgical Correction for Metopic Craniosynostosis: A 3D Photogrammetric Analysis of Cranial Vault Outcomes
Olivia E. Linden, BA; Vanessa M. Baratta, BA; Margaret M. Byrne, RN; Petra M. Klinge, MD, PhD; Stephen R. Sullivan, MD, MPH; Helena OB Taylor, MD, PhD
Warren Alpert Medical School of Brown University, Rhode Island Hospital, Hasbro Children's Hospital, Providence, RI
3:07 pm 85. Brain Electrophysiology in Craniosynostosis and Deformational Plagiocephaly
Jenny F. Yang, BS; Eric D. Brooks, BS; Peter W. Hashim, MD; Roberto Travieso, MD; Jordan Terner, MD; Hannah Reuman, BA; Karen Law, BA; Emily Levy, BA; Linda C. Mayes, PhD; James C. McPartland, PhD; John A. Persing, MD
Yale University School of Medicine, New Haven, CT
3:14 pm 86. Biomechanical Comparison of Lag Versus Bicortical Screw Fixation in Metacarpal Fractures
Priya Lewis, BA; Benjamin Gerke, BS; Zachary Filip, MD; Serkan Inceoglu, PhD; Jane Dhillon, MD; Mark Martin, MD, DMD
Loma Linda University, Loma Linda, CA
3:21 pm 87. An Automated Cleft Speech Evaluator Using Speech Recognition Software
James R. Seaward, FRCS(Plast.)1; Julie Cook, MS, CCC-SLP2; Cortney Van'T Slot, MS, CCC-SLP2; Rami Hallac, PhD2; Megan Vucovich, MD1; Alex A. Kane, MD1
1University of Texas Southwestern Medical Center, Dallas, TX, 2Children's Medical Center, Dallas, TX
3:28 pm 88. Spontaneous Forehead Remodeling after Posterior Vault Reconstruction in Sagittal Synostosis
Jose A. Gonzalez, BS; Olivia E. Linden, BA; Margaret E. Byrne, RN; Petra M. Klinge, MD, PhD; Stephen R. Sullivan, MD, MPH; Helena O. Taylor, MD, PhD
Brown University - Alpert Medical School, Providence, RI
3:35 pm 89. Optimization of Pathologic Fracture Healing after Radiotherapy Utilizing Amifostine in Combination with Deferoxamine
Hannah C. Ratliff, BS candidate; Alexis Donneys, MD, MS; Yekaterina Polyatskaya, MD; Noah S. Nelson, BS; Cheyenne A. Vasseli, BS; Sagar S. Deshpande, BS; Jose J. Rodriguez, MD; Joshua P. Spiegel, BS; Erin E. Page, BS; Tulsi Patel, BS; Steven R. Buchman, MD
University of Michigan, Ann Arbor, MI
3:42 pm 90. Craniofacial Anomalies Result from Morphogenetic Defects in Cellular Positional Cues as Revealed by Genetic Analysis of Wnt Signaling
Lucie J. Rochard, PhD; Stefanie Monica, BS; Yawei Kong, PhD; Michael Grimaldi, BS; Eric C. Liao, MD, PhD
Massachussets General Hospital, Boston, MA
3:49 pm 91. Autophagy Mediates Environment-Gene Interactions in Orofacial Cleft Pathogenesis
Lucie J. Rochard, PhD1; Edward Li, BS1; Christina Nguyen, BS1; James F. Gusella, PhD1; Richard Maas, MD, PhD2; Cynthia Morton, PhD2; Michael Talkowski, PhD1; Eric C. Liao, MD, PhD1
1Massachussets General Hospital, Boston, MA, 2Brigham and Women's Hospital, Boston, MA
3:56 pm 92. Using a Novel Transgenic Mouse to Identify Endochondral Ossification Precursor Cells and to Induce Bone Growth
Shawn Loder, BS; Shailesh Agarwal, MD; Cameron Brownley, BS; John Li, MD; Michael Sorkin, MD; Shuli Li, PhD; Jonathan Peterson, BA; Yuji Mishina, PhD; Benjamin Levi, MD
University of Michigan, Ann Arbor, MI
4:03 pm 93. A Novel Analogue of Oxysterol Promotes in vitro and in vivo Bone Regeneration
Kameron S. Rezzadeh, BA; Andres Segovia, MD; Akishige Hokugo, DDS, PhD; Reza Jarrahy, MD
UCLA Ronald Reagan Medical center, Los Angeles, CA
4:10 pm 94. Patient-Specific Tissue Engineered Constructs for Ear Reconstruction: Long Term (6 month) Results
Benjamin P. Cohen, BS1; Rachel C. Hooper, MD2; Jennifer Puetzer, PhD1; Rachel Nordberg, MEng1; Ope A. Asanbe, MD2; Peipei Zhang, PhD2; Lawrence J. Bonassar, PhD1; Jason A. Spector, MD, FACS2
1Cornell University, Ithaca, NY, 2Weill Cornell Medical College, New York, NY
4:17 pm 95. Combined Amifostine and Deferoxamine Therapy Preserves Biomechanics and Improves Union Rate in a Model of Distraction Osteogenesis Following Radiotherapy
Noah S. Nelson, BS; Yekaterina Polyatskaya, MD; Alexander R. Zheutlin, BS; Joseph E. Perosky, MS; Alexis Donneys, MD, MS; Jose J. Rodriguez, MD; Sagar S. Deshpande, BS; Kenneth M. Kozloff, PhD; Steven R. Buchman, MD
University of Michigan, Ann Arbor, MI
4:24 pm 96. Lymphatic Dysfunction Amplifies the Pathological Effects of Obesity in Skin Inflammation
Ira L. Savetsky, MD; Nicholas J. Albano, BS; Jason C. Gardenier, MD; Jeremy S. Torrisi, BA; Gabriela D. Garcia Nores, MD; Matthew D. Nitti, BA; Geoffrey E. Hespe, BS; Raghu P. Kataru, PhD; Babak J. Mehrara, MD, FACS
Memorial Sloan Kettering Cancer Center, New York, NY
3:00 - 4:30 pm Session 6 Group C
Elliott Bay
Moderators: Scott Hollenbeck, MD & Janice F. Lalikos, MD
3:00 pm 97. Prevention of Vein Intimal Hyperplasia with Photochemical Tissue Passivation in a Porcine Model
Saiqa I. Khan, MD; Harry M. Salinas, MD; Amanda Meppelink, BS; Michael C. McCormack, MBA; Mark A. Randolph, MAS; Robert W. Redmond, PhD; William G. Austen, Jr., MD
Massachusetts General Hospital - Harvard Medical School, Boston, MA
3:07 pm 98. Alternatively Activated M2 Macrophages Improve Autologous Fat Graft Survival via Induction of Angiogenesis in a Preclinical Model.
Simon Gebremeskel, BScH; Kyle Phipps, PhD; Joshua Gillis, MD; Paul Hong, MD, FRCSC; Brent Johnston, PhD; Michael Bezuhly, MD, FRCSC
Dalhousie University, Halifax, NS, Canada
3:14 pm 99. Understanding Melanoma Pathogenesis By Elucidating the Gene Regulatory Network Of Melanocyte Progenitors.
Stefanie Monica, BS1, Richard Harland, PhD2, Eric Liao, MD,PhD1
1Massachusetts General Hospital, Boston, MA, 2University of California, Berkeley, Berkeley, CA
3:21 pm 100. Creation and Validation of a Condition-Specific VTE Risk Assessment Tool for Open Ventral Hernia Repair Patients
Christopher J. Pannucci, MD MS1, Marten N. Basta, BA2, John P. Fischer, MD2, Stephen J. Kovach, MD2
1University of Utah, Salt Lake City, UT, 2University of Pennsylvania, Philadelphia, PA
3:28 pm 101. Amifostine Prophylaxis Ameliorates Radiation-induced Injury in A Murine Model of Expander-based Breast Reconstruction
Yekaterina Polyatskaya, MD; Noah S. Nelson, BS; Jose J. Rodriguez, MD; Alexander R. Zheutlin, BS; Sagar S. Deshpande, BS; Peter A. Felice, MD; Alexis Donneys, MD, MS; Steven R. Buchman, MD
University of Michigan, Ann Arbor, MI
3:35 pm 102. Developing a Noninvasive High-efficacy Technique for the Treatment of Infantile Hemangioma using a Nanoparticle-Conjugated Delivery System
Hakan Orbay, MD, PhD; Lindsey Harrison, BS; Kamaljit Devi, BS; Yuanpei Li, PhD; Wenwu Xiao, PhD; Kit Lam, MD, PhD; David E. Sahar, MD
UCDavis, Sacramento, CA
3:42 pm 103. PUMA Regulates Radiation Induced Fibrosis by Activating Epithelial to Mesenchymal Transition through Snail1 Expression
Nicholas Brownstone, BA, William Hambley, BA, Karan Mehta, BS, Nakul Rao, MD, Chin Park, MD, Rohini Kadle, BS, Anna Zhou, BA, Camille Kim, BS, Abigail Sartor, BA, Piul Rabbani, PhD, Pierre Saadeh, MD, Daniel Ceradini, MD
NYU Langone Medical Center, New York, NY
3:49 pm 104. Co-Implantation of Auricular Chondrocytes and Mesenchymal Stem Cells for the Generation of Auricular Elastic Neocartilage: Strategy Towards the Translation of Tissue Engineered Ears
Ope A. Asanbe, MD1; Benjamin P. Cohen, BS2; Peipei Zhang, PhD1; Wilmina N. Landford, BA1; Adam M. Jacoby, BA1; Lawrence J. Bonassar, PhD2; Jason A. Spector, MD, FACS1
1Weill Cornell Medical College, New York, NY, 2Cornell University, Ithaca, NY
3:56 pm 105. Efficacy and Economic Advantage of Exparel Intercostal Nerve Blocks for Pain Management in 1st Stage Implant Based Breast Reconstruction Patients
Suzette G. Miranda, MD; Thomas Gallagher, BA; Hakim K. Said, MD
University of Washington, Seattle, WA
4:03 pm 106. 9-Cis-Retinoic Acid Ameliorates Surgically Induced Lymphedema In The Mouse Hindlimb Model
Athanasios Bramos, MD; Young-Kwon Hong, PhD; Alex K. Wong, MD
Keck School of Medicine of USC, Los Angeles, CA
4:10 pm 107. Efficient Topical Gene Silencing via Self-Assembling Engineered Lipoproteoplex
Anna T. Zhou, BA1; William Rifkin, BS1; Haresh More, MTech2; Nikita Srivastava, BS2; Muhammad H. Junejo, BS1; Rohini L. Kadle, BS1; Camille Kim, BS1; Rita A. Sartor, BA1; Nicholas D. Brownstone, BA1; Jin K. Montclare, PhD2; Pierre B. Saadeh, MD1; Piul S. Rabbani, PhD1; Daniel J. Ceradini, MD1
1New York University, New York, NY, 2Polytechnic Institute of New York University, New York, NY
4:17 pm 108. Vascular Endothelial Growth Factor Signaling is affected by Changes in the ß-Adrenergic Receptor Pathways in Hemangioma Stem Cells
Alison Kitajewski, BA; Justin Kung, BA; Andrew K. Edwards, PhD; Carrie J. Shawber, PhD; Jan K. Kitajewski, PhD; June K. Wu, MD
Columbia University, New York, NY
4:30 - 5:30 pm Poster Viewing Reception
Puget Sound
7:00 - 9:00 pm Members Dinner
The Flight Museum
 

Saturday, May 16, 2015

7:30 am - 12:30 pm Registration
Cascade Ballroom Foyer
7:30 am - 12:00 pm Speaker Ready Room
Cascade Ballroom Foyer
7:30 - 10:30 am Exhibits
Cascade Ballroom Foyer
7:30 - 8:30 am Continental Breakfast with Exhibitors
Cascade Ballroom Foyer
7:30 - 8:30 am Mentorship Breakfast
Cascade Ballroom I
8:30 - 10:00 am Session 7 Group A
Cascade Ballroom I
Moderators: Brian Carlsen, MD; Damon Cooney, MD, PhD & Christine Radtke, MD, PhD
8:30 am 109. Reconstruction of Abdominal Wall Defects Using Neurotized Vascularized Composite Allografts
Justin M. Broyles, MD; Karim A. Sarhane, MD, MSc; Sami H. Tuffaha, MD; Damon S. Cooney, MD, PhD; W.P. Andrew Lee, MD; Gerald Brandacher, MD; Justin M. Sacks, MD
The Johns Hopkins University School of Medicine, Baltimore, MD
8:37 am 110. Cellular Senescence Onset Coincides with Axonal Regenerative Arrest in Long Acellular Nerve Grafts
Louis H. Poppler, MD; Xueping Ee, MD; Lauren Prange, BS; Gwendolyn Hoben, MD; Daniel A. Hunter, RA; Ying Yan, MD, PhD; Sheila Stewart, PhD; Susan E. Mackinnon, MD; Matthew D. Wood, PhD
Washington University in St. Louis School of Medicine, St. Louis, MO
8:44 am 111. Notch Signaling In Senescent Schwann Cells: A Target For Improving Nerve Regeneration
Gwendolyn M. Hoben, MD, PhD; Xueping Ee, MD; Lauren Prange, BS; Daniel Hunter, RA; Amy M. Moore, MD; Sheila Stewart, PhD; Susan E. Mackinnon, MD; Matthew D. Wood, PhD
Washinton University School of Medicine, St.Louis, MO
8:51 am 112. Evaluation of Viability, Structural Integrity and Functional Outcome after Whole Eye Transplantation
Yang Li, MD, PhD1; Chiaki Komatsu, MD1; Bo Wang, BS1; Maxine R. Miller, MD1; Hongkun Wang, MD1; Yolandi van der Merwe, BEng1; Leon C. Ho, BEng1; Nataliya Kostereva, PhD1, Wensheng Zhang, MD, PhD1; Bo Xiao, MD, PhD1; Edward H. Davidson, MA, MBBS1; Mario G. Solari, MD1; Michael B. Steketee, PhD1; Shuzhong Guo, MD, PhD2; Lawrence Kagemann, MD1; Gadi Wollstein, MD1; Joel S. Schuman, MD1; Kevin C. Chan, PhD1; Vijay S. Gorantla, MD, PhD1; Kia M. Washington, MD1
1University of Pittsburgh, Pittsburgh, PA, 2Fourth Military Medical University, Xi'an, China
8:58 am 113. Vascularized Bone Marrow Transplantation As A New Approach For Bone Marrow Transplantation
Yingjun Su, MD, PhD; Jianwu Chen, MD; Shuzhong Guo, MD, PhD
Department of Plastic and Reconstructive Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China
9:05 am 114. Defining The Role Of Skin And Mucosal Biopsy In Facial Allotransplantation.
Arif Chaudhry, MD1; Michael Sosin, MD2; Branko Bojovic, MD2; Michael R. Christy, MD2; Cinthia B. Drachenberg, MD3; Eduardo D. Rodriguez, DDS, MD1
1New York University Langone Medical Center, New York, NY, 2R Adams Cowley Shock Trauma Center, Baltimore, MD, 3Univeristy of Maryland Medical Center, Baltimore, MD
9:12 am 115. Development of a Brain Body Interface for Upper Limb Reanimation: Selective Muscle Activation with a Chronically Implanted Nerve Cuff Electrode on the Sciatic Nerve
Neil Fairbairn, MD1; Wasim Q. Malik, PhD2; Neelakantan Sunder, MD1; Robert Ajemian, PhD2; Ashley Turza, PhD2; Victoria Vega, PhD2; Jeena Easow, MD1; Emilio Bizzi, MD, PhD2; Emory Brown, MD, PhD2; Jonathan M. Winograd, MD1
1Massachusetts General Hospital, Boston, MA, 2Massachusetts Institute of Technology, Cambridge, MA
9:19 am 116. The Impact and Mechanisms of Antibody-Mediated Rejection in Vascularized Composite Allotransplantation
Devin T. Miller, BS; Denver Lough, MD, PhD; Barbara Kern, MD; Georg J. Furtmüller, MD; Giorgio Raimondi, PhD; W.P. Andrew Lee, MD; Zhaoli Sun, MD, PhD; Gerald Brandacher, MD
The Johns Hopkins School of Medicine, Baltimore, MD
9:26 am 117. Microenvironmental Cues Enhance Indoleamine 2,3-dioxygenase Expression to Facilitate Mesenchymal Stem Cell-Mediated Immunosuppression
Rohini L. Kadle, BS; Marc A. Soares, MD; Nakul Rao, MD; April Duckworth, MD; Chin Park, MD; Joshua David, BS; Christopher D. Lopez, BA; Anna Zhou, BA; Nicholas Brownstone, BA; Rita Abigail Sartor, BS; Camille Kim, BS; Piul S. Rabbani, PhD; Daniel J. Ceradini, MD
NYU, New York, NY
9:33 am 118. Monoclonal Antibody (Herceptin) Mediated Enhancement of Peripheral Motor and Sensory Neuron Regeneration Operates through a Potential New Pathway Involving ErbB2 and the Epidermal Growth Factor Receptor (ErbB1)
Mike Hendry, MD, MSc1; Eva Placheta, MD2; Cecilia Alvarez-Veronesi, MASc1; Tessa Gordon, PhD1; Gregory Borschel, MD1
1University of Toronto, Toronto, ON, Canada, 2Medical University of Vienna, Vienna, Austria, Austria
9:40 am 119. Development of a Non-invasive Diagnostic and Predictive Tool for Acute Rejection in Vca Using Differential Cytokine Profiling
Nakul Rao, MD; Chin Park, MD; Piul Rabbani, PhD; Daniel Ceradini, MD; Rohini Kadle, BS; Anna Zhou, BA; Nicholas Brownstone, BA
NYU, New York, NY
9:47 am 120. A Critical Analysis of Peripheral Nerve Regeneration in a Chronic Denervation Rat Model Using a Sustained Biomaterial-Based Delivery of GDNF, Chondroitinase, and GDNF+Chondroitinase Growth Factors
Karim A. Sarhane, MD, MSc; Sami H. Tuffaha, MD; Kellin Krick, PhD candidate; Chris Cashman, MD, PhD candidate; Joshua D. Budihardjo, B.Sc; Justin M. Broyles, MD; Russel Martin, PhD candidate; James Abraham, MA; Zuhaib Ibrahim, MD; Ruifa Mi, MD, PhD; Damon S. Cooney, MD, PhD; Ahmet Hoke, MD, PhD; WP Andrew Lee, MD; Hai-Quan Mao, PhD; Gerald Brandacher, MD
Johns Hopkins University, Baltimore, MD
8:30 - 10:00 am Session 7 Group B
Cascade Ballroom II
Moderators: Jason H. Ko, MD; Howard Levinson, MD, FACS & Jason A. Spector, MD
121. WITHDRAWN
8:30 am 122. RNA Sequencing for Identification of Differentially Expressed Non-Coding Transcripts During Adipogenic Differentiation of Adipose-Derived Stromal Cells
Anna Luan, MS; Kevin J. Paik, AB; Jiang Li, MS; Elizabeth R. Zielins, MD; David A. Atashroo, MD; Andrew Spencley, BS; Arash Momeni, MD; Michael T. Longaker, MD, MBA; Kevin C. Wang, MD, PhD; Derrick C. Wan, MD
Stanford University School of Medicine, Stanford, CA
8:37 am 123. Enhancing Outcomes Following Neonatal Nerve Injury with N-acetyl Cysteine
Daniel Demsey, MD; Joseph Catapano, MD; David Scholl, BSc; Cameron Chiang, BSc; Tessa Gordon, PhD; Gregory Borschel, MD
The Hospital for Sick Children, Toronto, ON, Canada
8:44 am 124. Mitigation Of Hypertrophic Scar Contraction And Stiffening Via An Elastomeric Biodegradable Scaffold
Mohamed M. Ibrahim, MD1; Elizabeth R. Lorden, BS2; Kyle J. Miller, BA1; Latif Bashirov, MD1; Ellen Hammett, BS2; Manuel Medina, MD1; Youngmee Jung, BS3; Ali Rastegarpou, MD1; Angelica M. Selim, MD4; Kam W. Leong, PhD5; Howard Levinson, MD1
1The Division of Plastic and Reconstructive Surgery, Department of Surgery, Duke University School of Medicine, Durham, NC, 2Department of Biomedical Engineering, Duke University, Durham, NC, 3Korea Institute of Science and Technology Biomaterials Research Center, Korea, Korea, Republic of, 4Duke University Medical Center, Department of Pathology, Durham, NC, 5Columbia University, Department of Biomedical Engineering, New York, NY
8:51 am 125. Development of a Medical Device for Clinical Translation of a Novel PEG Fusion Method for Immediate Physiological Recovery after Peripheral Nerve Injury
David C. Riley, BS1; Curt A. Deister, PhD2; Richard B. Boyer, BS1; Charlie L. Rodriguez-Feo, BS1; Tu-Anh N. Ha, BS1; Bruce R. Shack, MD1; Wesley P. Thayer, MD/PhD1
1Vanderbilt University Medical Center, Nashville, TN, 2Axogen, Gainesville, FL
8:58 am 126. An Electrospun Fiber-Hydrogel Composite with Interfacial Bonding for Soft Tissue Regeneration in vivo
Georgia C. Yalanis, MSc1; Sashank Reddy, MD1; Russ Martin, BS2; Jisuk Choi, PhD2; Gerald Brandacher, MD1; Hai-Quan Mao, PhD2; Justin M. Sacks, MD1
1Johns Hopkins University School of Medicine, Baltimore, MD, 2Johns Hopkins University Whiting School of Engineering, Baltimore, MD
9:05 am 127. Sustained Release of FK506 from a Polymeric Drug Delivery System for the Treatment of Peripheral Nerve Injury
Kasra Tajdaran, MASc1; Matthew D. Wood, PhD2; Molly S. Shoichet, PhD1; Tessa Gordon, PhD1; Gregory H. Borschel, MD, FACS, FAAP1
1University of Toronto, Toronto, ON, Canada, 2Washington University, St. Louis, MO
9:12 am 128. Biopatterned Recombinant Human Bone Morphogenetic Protein 2 Does Not Induce Pansynostosis or Growth Restriction in the Immature Craniofacial Skeleton
Sameer Shakir, BS1; Osama Basri, DMD1; James J. Cray, PhD2; Sanjay Naran, MD1; Darren M. Smith, MD3; Zoe M. MacIsaac, MD1; Evan B. Katzel, MD1; Weinberg M. Seth, PhD1; Mark P. Mooney, PhD1; Joseph E. Losee, MD1; Cooper M. Greg, PhD1
1University of Pittsburgh, Pittsburgh, PA, 2Medical University of South Carolina, Charleston, SC, 3Hospital for Sick Children, Toronto, ON, Canada
9:19 am 129. Effects of Growth Hormone Therapy on Axonal Regeneration, Muscle Atrophy, Schwann Cell Proliferation and End-Organ Reinnervation Following Nerve Injury and Repair
Sami Tuffaha, MD; Joshua Budihardjo, BSc; Karim Sarhane, MD; Mohammed Khosheim, MD; Diana Song, MD; Justin Broyles, MD; Roberto Salvatori, MD; Kenneth Means, MD; James Higgins, MD; Jaimie Shores, MD; Ahmet Hoke, MD; Damon Cooney, MD PhD; W.P. Andrew Lee, MD; Gerald Brandacher, MD
Johns Hopkins Medical Institutions, Baltimore, MD
9:26 am 130. Tissue Engineered, 3D Collagen Microsphere Scaffold (MSS) Expedites Cellular Invasion and Neovascularization
Peipei Zhang, MD, PhD; Ope Asanbe, MD; Wilmina Landford, MD; Adam Jacoby, BA; Rachel Hooper, MD; Abraham Stroock, PhD; Jason Spector, MD, FACS
Weill Cornell Medical College, New York, NY
9:33 am 131. Muscle-Specific ECM Derived Hydrogel for 3D Printing Facilitates Differentiation of Adipose Derived Stem Cells into Muscle Cells
Solmaz N. Niknam-Bienia, MD, MHA; Alexandra L. Rutz, MS; Sumanas W. Jordan, MD, PhD; Ian Chow, BS; Thomas A. Mustoe, MD; Ramille N. Shah, PhD; Seok Jong Hong, PhD; Robert D. Galiano, MD
Northwestern University, Chicago, IL
9:40 am 132. A Multifactorial Histologic Analysis of the Foreign Body Response to Intradermal and Subcutaneous Implants
Eugenia H. Cho, BS1; Alina Boico, BS1; Lin Liao1; Janna K. Register, PhD1; Natalie A. Wisniewski, PhD2; Kristen Helton, PhD2; Tuan Vo-Dinh, PhD1; Gregory Palmer, PhD1; Bruce Klitzman, PhD1
1Duke University, Durham, NC, 2PROFUSA Corp, San Francisco, CA
8:30 - 10:00 am Session 7 Group C
Elliott Bay
Moderators: Henry C. Hsia, MD & Derrick C. Wan, MD
8:30 am 133. Natural Killer Cells Promote Differentiation of Human Adipose-Derived Stem Cells in vitro
Kameron S. Rezzadeh, BA; Akishige Hokugo, DDS, PhD; Anahid Jewett, PhD, MPH; Anna Kozlowska, PhD; Andres Segovia, MD; Patricia Zuk, PhD; Zheyu Zhang, BA; Reza Jarrahy, MD
UCLA Ronald Reagan Medical center, Los Angeles, CA
8:37 am 134. Adipose-derived Stem Cells after Paclitaxel Treatment Demonstrate Decreased Function and Suppression of Breast Cancer Cell Viability
William M. Harris, MD; Michael A. Plastini, MD; Telisha Ortiz, MD; Nikolas Kappy, MD; Jefferson Benites, BS; Shaohua Chang, PhD; A. Lelani Fahey, MD; Martha S. Matthews, MD; Jeffrey P. Carpeneter, MD; Spencer Brown, PhD; Ping Zhang, PhD
Department of Surgery- Cooper University Hospital and Cooper Medical School of Rowan University, Camden, NJ
8:44 am 135. Human Adipose Tissue-Derived Stromal/Stem Cells Promote Migration and Early Metastasis of Head & Neck Cancer Xenografts
Walter J. Joseph, III, BS1; Eduardo A. Lacayo, MD2; Mei Sheng, MD, PhD2; Muralidharan Anbalagan, PhD2; Jeffrey M. Gimble, MD, PhD3; Ryan K. Jones, MA2; Paul L. Friedlander, MD2; Brian G. Rowan, PhD2; Ernest S. Chiu, MD1
1NYU Langone Medical Center, New York, NY, 2Tulane University School of Medicine, New Orleans, LA, 3Louisiana State University, Baton Rouge, LA
8:51 am 136. Simple, Non-invasive and Effective New Generation Vascular and Tissue Regenerative Endothelial Progenitor Cell Therapy for Non-healing Diabetic Wounds
Rica Tanaka, MD, PhD1; Kayo Arita, PhD1; Satoshi Fujimura, PhD1; Kayoko Okada, PhD1; Makiko Kado, MD1; Takayuki Asahara, MD, PhD2; Hiroshi Mizuno, MD, PhD1
1Juntendo University School of Medicine, Tokyo, Japan, 2Tokai University School of Medicine, Isehara, Japan
8:58 am 137. Fibromodulin Reprogrammed Cells-based Bone Regeneration
Zhong Zheng, PhD1; Tara Aghaloo, DDS, MD, PhD1; Chen-shuang Li, DDS1; Pu Yang, DDS, MD, PhD1; Soonchul Lee, MD, PhD2; Jin-Hee Kwak, DDS, MS1; Ali Zarringhalam, BS1; Maxwell Murphy, MS1; Kang Ting, DMD, DMedSci1; Chia Soo, MD1
1UCLA, Los Angeles, CA, 2CHA Univeristy, Gyeongghi-do, Korea, Republic of
9:05 am 138. External Volume Expansion and Fat Grafting after Post Mastectomy Radiation Therapy: Increased Skin Angiogenesis and Proliferation May Improve Fat Graft Based Soft Tissue Reconstruction
Jorge Lujan-Hernandez, MD1, Michael S. Chin, MD1, Dylan J. Perry, B.A.1, Ava G. Chappell, BA1, Oksana O. Babchenko, BS1, Elizabeth Bannon, MS1, Luca Lancerotto, MD2, Yuan Chyuan Lo, PhD1, Thomas J. Fitzgerald, MD1, Janice F. Lalikos, MD1
1University of Massachusetts Medical School, Worcester, MA, 2University of Padova, Padova, Italy
9:12 am 139. Novel Preparation Method for The Therapeutic Micro-spheroids Of Adipose-derived Stromal Cells (ASCs): Three-dimensional Floating Culture In Non-cross-linked Hyaluronic Acid (HA) Gel
Jingwei Feng, MD; Kazuhide Mineda, MD; Kentaro Doi, MD; Shinichiro Kuno, MD; Kahori Kinoshita, MD; Koji Kanayama, MD; Kotaro Yoshimura, MD
University of Tokyo, Tokyo, Japan
9:19 am 140. Ultrasound Assisted Liposuction Does not Compromise The Regenerative Potential of Ascs
Dominik Duscher, MD1,2; Anna Luan, MS2; David Atashroo, MD2; Zeshaan N. Maan, MBBS, MS2; Elizabeth R. Zielins, MD2; Kevin Paik, BA2; Alexander J. Whittam, BS2; Michelle Lin, BS2; Graham G. Walmsley, BA2; Michael S. Hu, MD, MPH, MS2; Manfred Schmidt, MD1; Georg M. Huemer, MD, MBA, MS1; Derrick C. Wan, MD2; Michael T. Longaker, MD, MBA2; Geoffrey C. Gurtner, MD, FACS2
1Johannes Keppler University, Division of Plastic Surgery, Linz, Austria, 2Stanford University, Division of Plastic Surgery, Stanford, CA
9:26 am 141. Malar 3D Lipotopography: Relating Fat Grafting to the Cheek and Topographical Surface Changes
Carrie Stern, MD1, Jillian E. Schreiber, BA1, Matthew E. Doscher, MD1, Jeremy S. Nikfarjam, MD1, Evan S. Garfein, MD1, Elizabeth B. Jelks, MD2, Glenn W. Jelks, MD2, Oren M. Tepper, MD1
1Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY, 2NYU Langone Medical Center, New York, NY
9:33 am 142. A Microbiologic Comparison of Acellular Dermal Matrices as an Aseptic Reconstructive Material and a Scaffold for Stem Cell In-growth
Shaun D. Mendenhall, MD1; Tim H.F. Daugherty, MS1; Nicole M. Cosenza, MS1; Katherine E. McKenna, MD1; Ryan W. Schmucker, MD1; Joel D. Reichensperger, BS1; Ashim Gupta, PhD1; Janak Koirala, MD; MPH1; Paul S. Cederna, MD2; Michael W. Neumeister, MD1
1Southern Illinois University School of Medicine, Springfield, IL, 2University of Michigan School of Medicine, Ann Arbor, MI
9:40 am 143. Characterization And Transplantation Of Human Muscle Stem Cells For Reconstructive Applications.
Xiaoti Xu, MD1; Karlijn Wilschut, PhD1; Gayle Kouklis, BS1; Hua Tian, PhD1; Robert Hesse, BS1; Jason H. Pomerantz, MD2
1Department of Surgery, Division of Plastic and Reconstructive Surgery, University of California San Francisco, San Francisco, CA, 2Departments of Surgery and Orofacial Sciences, Division of Plastic and Reconstructive Surgery, Craniofacial and Mesenchymal Biology Program, Eli and Edythe Broad Center of Regeneration Medicine, University of California San Francisco, San Francisco, CA
9:47 am 144. Differential Oxygen Tension and Environmental Inflammatory Conditions Optimize Mesenchymal Stem Cell Fate and Immunosuppressive Potential
Rohini L. Kadle, BS; Marc A. Soares, MD; Nakul Rao, MD; April Duckworth, MD; Chin Park, MD; Joshua David, BS; Christopher D. Lopez, BA; Anna Zhou, BA; Nicholas Brownstone, BA; Rita Abigail Sartor, BS; Camille Kim, BS; Piul S. Rabbani, PhD; Daniel J. Ceradini, MD
NYU, New York, NY
10:00 - 10:30 am Coffee with Exhibitors
Cascade Ballroom Foyer
10:30 am - 11:40 am Session 8 Group A
Cascade Ballroom I
Moderators: Eric C. Liao, MD, PhD & Alex K. Wong, MD
10:30 am 145. Lymph Node Transfer Restores Immune Responses in a Mouse Model of Lymphedema
Walter J. Joseph, III, BS; Seth Z. Aschen, BS; Daniel A. Cuzzone, MD; Jason C. Gardenier, MD; Swapna Ghanta, MD; Nicholas J. Albano, BS; Ira L. Savetsky, MD; Jeremy S. Torrisi, BA; Babak J. Mehrara, MD
MSKCC, New York, NY
10:37 am 146. Short Hairpin RNA Silencing of PHD-2 Improves Neovascularization and Functional Outcomes in Diabetic Wounds and Ischemic Limbs
Kevin J. Paik, AB1; Zeshaan Maan, MD1; Shane D. Morrison, MS1; Hsin-Han Chen, MD1; Robert Rennert, BS1; Michael Sorkin, MD1; Dominik Duscher, MD1; Michael T. Chung, BS1; David Atashroo, MD1; Michael S. Hu, MD1; Shuli Li, MD, PhD1; Kshemendra Senarath-Yapa, MD1; Adrian McArdle, MD1; Elizabeth A. Brett, MS1; Anna Luan, MS1; Ruth Tevlin, MD1; Elizabeth R. Zielins, MD1; Wan Xing Hong, MS1; Graham Walmsley, BS1; Christopher Duldulao, BS1; Taylor Wearda, BS1; Owen Marecic, BS1; Joseph C. Wu, MD PhD2,3; Geoffrey C. Gurtner, MD1; Michael T. Longaker, MD, MBA1,4; Derrick C. Wan, MD1
1Hagey Laboratory for Pediatric Regenerative Medicine, Department of Surgery, Plastic and Reconstructive Surgery Division, Stanford University School of Medicine, Stanford, CA, 2Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA, 3Department of Radiology, Stanford University School of Medicine, Stanford, CA, 4Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA
10:44 am 147. A Transdermal Drug Delivery System for Deferoxamine for the Prevention and Treatment of Diabetic Wounds
Dominik Duscher, MD1,2; Alexander J. Whittam, BS1; Zeshaan N. Maan, MBBS, MS1; Mohammed Inayatullah, PhD1; Janos Barrera, BS1; Arnetha J. Whitmore, BA1; Yixiao Dong, PhD1; Jayakumar Rajadas, PhD1; Geoffrey C. Gurtner, MD, FACS1
1Stanford University, Division of Plastic Surgery, Stanford, CA, 2Johannes Keppler University, Division of Plastic Surgery, Linz, Austria
10:51 am 148. Obesity But Not High Fat Diet Impairs Lymphatic Function
Gabriela D. Garcia Nores, MD1; Daniel A. Cuzzone, MD2; Jason C. Gardenier, MD1; Ira L. Savetsky, MD1; Jeremy S. Torrisi, B.A.1; Matthew D. Nitti, BA1; Geoffrey E. Hespe, BS1; Raghu P. Kataru, PhD1; Babak J. Mehrara, MD1
1Memorial Sloan Kettering Cancer Center, New York, NY, 2New York University Hospital Center, New York, NY
10:58 am 149. Perilymphatic Inflammation and iNOS Production Play a Key Role in the Regulation of Lymphatic Dysfunction in Obesity
Jeremy S. Torrisi, BA; Daniel A. Cuzzone, MD; Geoffrey E. Hespe, BS; Matthew D. Nitti, BA; Jason C. Gardenier, MD; Ira L. Savetsky, MD; Gabriela Garcia Nores, MD; Raghu Kataru, PhD; Babak J. Mehrara, MD, FACS
Memorial Sloan Kettering Cancer Center, New York, NY
11:05 am 150. Phosphodiesterase 5 Inhibition Mitigates I-r Injury in a Model of Vascularized Composite Allotransplantation
Marc A. Soares, MD; Nakul Rao, MD; Chin Park, MD; Piul S. Rabbani, PhD; Abby Sartor, BA; Pierre B. Saadeh, MD; Daniel J. Ceradini, MD
NYU, New York, NY
11:12 am 151. Tlr3 Activation Links Damage Sensing to Epimorphic Regeneration in the Skin
Sashank K. Reddy, MD, PhD1; Amanda Nelson, PhD2; Emily Chang, BA1; Tabetha Ratliff, MA1; Adiya Katseff, BA1; Sydney Resnik, BA1; Lloyd S. Miller, MD, PhD1; Luis A. Garza, MD, PhD1
1Johns Hopkins University, Baltimore, MD, 2Pennsylvania State University, Hershey, PA
11:19 am 152. Attenuation of Autophagy via local SGK-1 Inhibition in SCC of the Head and Neck May Sensitize to Cisplatin Therapy
Henrik O. Berdel, MD1; Jun Liu, BS2; Mahmood Mozaffari, PhD2; Jack C. Yu, MD2; Babak Baban, PhD2
1Palmetto Health / University of South Carolina, Columbia, SC, 2Georgia Regents University, Augusta, GA
11:26 am 153. The Investigation of Transendothelial Migration and Breast Cancer Metastasis Utilizing A Tissue Engineered, Ex Vivo Three Dimensional Vascularized Platform
Rachel C. Hooper, MD1; Ope A. Asanbe, MD1; Wilmina N. Landford, BA1; Adam M. Jacoby, BA1; Peipei Zhang, PhD1; Hector L. Osoria, BS1; Claudia Fischbach, PhD2; Jason A. Spector, MD, FACS1
1Weill Cornell Medical College, New York, NY, 2Cornell University, Ithaca, NY
11:33 am 154. Chronic Wounds have Surrounding Regions of Lymphatic Dysfunction
Jeremy S. Torrisi, BA; Ira L. Savetsky, MD; Jason C. Gardenier, MD; Gabriela Garcia Nores, MD; Matthew D. Nitti, BA; Geoffrey E. Hespe, BS; Raghu Kataru, PhD; Babak J. Mehrara, MD, FACS
Memorial Sloan Kettering Cancer Center, New York, NY
10:30 am - 11:50 pm Session 8 Group B
Cascade Ballroom II
Moderators: Benjamin Levi, MD & Brian Rinker, MD
10:30 am 155. Hypoxia Preconditioned Plasma (HPP) and its Role in promoting Angiogenesis-supported Wound Regeneration
P.Niclas Broer, MD; Ektoras Hadjipanayi, MD, PhD; Anna T. Bauer, MD; Philipp Moog, MS; Sarah von Isenburg, MD; Milomir Ninkovic, MD, PhD; Hans-Günther Machens, MD, PhD; Arndt F. Schilling, MD, PhD
Klinikum rechts der Isar , Technische Universität München, München, Germany
10:37 am 156. Optimizing Timing and Targeting of Bone Morphogenetic Protein Receptor One to Treat Heterotopic Ossification with Novel Kinase Inhibitors and Ligand Traps
John Li, MD1; Shailesh Agarwal, MD1; Shawn Loder, BS1; Cameron Brownley, BS1; Jonathan Peterson, BS1; Kavitha Ranganathan, MD1; Paul S. Cederna, MD1; Eboda Oluwatobi, BS1; Agustin Mohedas, PhD2; Paul Yu, MD2; Benjamin Levi, MD1
1University of Michigan, Ann Arbor, MI, 2Brigham and Womens Hospital, Boston, MA
157. WITHDRAWN
10:44 am 158. Novel Implantable Optical Oxygen Monitor to Detect Flap Viability
Mohamed M. Ibrahim, MD; Bruce Klitzman, PhD
The Division of Plastic and Reconstructive Surgery, Department of Surgery, Duke University School of Medicine, Durham, NC
10:51 am 159. Combining Preoperative CTA Mapping of the Peroneal Artery and Its Perforators with Computer-Generated Patient-Specific Surgical Guides for Free Fibula Flap Reconstruction of Complex Head and Neck Defects
Noopur Gangopadhyay, MD; Mark W. Villa, MD; Edward I. Chang, MD; Jesse C. Selber, MD; Elizabeth S. Craig, MD; Jessie Liu, PhD; Patrick B. Garvey, MD
UT MD Anderson Cancer Center, Houston, TX
10:58 am 160. Muscle-Sparing Latissimus Dorsi Myocutaneous Pedicled Flaps with Extended Transversely Oriented Skin Paddles are a Reliable Alternative to Thoracodorsal Artery Perforator Flaps
Yin Kan Hwee, MD; Pedro Vieira, ME; Christopher Brooks, MD; Yoav Barnavon, MD
Cleveland Clinic Florida, Weston, FL
11:05 am 161. Operative Outcomes with CT-Guided Virtual Surgical Modeling for Mandibular Reconstruction with Osteocutaneous Free Flaps?
Eric I. Chang, MD; Neal S. Topham, MD
Fox Chase Cancer Center, Rockledge, PA
11:12 am 162. Changes in Skin Vascularity in a Murine Model for Post-Mastectomy Radiation
Jose J. Rodriguez, MD, Theodore A. Kung, MD, Yekaterina Polyatskaya, MD, Noah S. Nelson, BS, Yao Wang, MD, Sagar S. Deshpande, BS, Alexander R. Zheutlin, BS, Alexis Donneys, MD, Steven R. Buchman, MD, Adeyiza O. Momoh, MD
University of Michigan, Ann Arbor, MI
11:19 am 163. Topical Deferoxamine Penetrates the Dermis and Increases Cutaneous Vascularity: The Development of a Topical Therapy for Radiation Soft Tissue Injury
Kasandra R. Hanna, MD; Alexander F. Mericli, MD; Patrick S. Cottler, PhD; Lisa S. Salopek, LVT, Yalin Wang, PhD; Jessica S. Wang, BS; Madeline M. Stovall, BA; George T. Rodeheaver, PhD; Kant Y. Lin, MD
University of Virginia, Charlottesville, VA
11:26 am 164. The Impact of the Adaptive Immune System On Ectopic Bone Formation
Kavitha Ranganathan, MD; Shuli Li, PhD; Shawn Loder, BS; Cameron Brownley, BS; Shailesh Agarwal, MD; Casey Kraft, BS; Oluwatobi Eboda, BS; Jonathan Peterson, BS; Paul S. Cederna, MD; Steven R. Buchman, MD; Benjamin Levi, MD
University of Michigan, Ann Arbor, MI
11:33 am 165. Profunda Artery Perforator Flap Perforasome Territories: Implications of Vascular Anatomy for Optimal Flap Design in Reconstructive Microsurgery
Anita T. Mohan, MRCS, MBBS, BSc1; Lin Zhu, MD2; Charalambos Rammos, MD2; Gregory Michalak, PhD2; Nirusha Lachman, PhD2; Steve Moran, MD2; Michel Saint-Cyr, MD2
1Mayo Clinic, Rochester, MN, 2Mayo Clinic, Rochester, MN
11:40 am 166. Appraisal Of Perforasomes And Venosomes Of Perforators In Bilateral Diep Breast Reconstruction Using Updated SpyQ Analysis
Anita T. Mohan, MRCS, MBBS, BSc; Lin Zhu, MD; Samir Mardini, MD; Steven Moran, MD; Michel Saint-Cyr, MD
Mayo Clinic, Rochester, MN
10:30 am - 12:00 pm Session 8 Group C
Elliott Bay
Moderators: Timothy W. King, MD, PhD & Keith T. Paige, MD
10:30 am 167. Tissue Inhibitor Of Metalloproteinase-2 Suppresses Collagen Synthesis Within Keloids
Teruyuki Dohi, MD; Koichi Miyake, MD, PhD; Masayo Aoki, MD, PhD; Rei Ogawa, MD, PhD; Satoshi Akaishi, MD, PhD; Takashi Okada, MD, PhD; Hiko Hyakusoku, MD, PhD
NIppon Medical School, Tokyo, Japan
10:37 am 168. Thrombospondin-1 And CD47 Signaling Regulate Healing Of Thermal Injury In Mice
Justin B. Maxhimer, MD1; Hubert Shih, MD2; David Soto-Pantoja, PhD3; David Roberts, PhD3
1UCLA Medical Center, Los Angeles, CA, 2Stanford School of Medicine, Palo Alto, CA, 3National Institutes of Health, Bethesda, MD
10:44 am 169. Calcium Entry Via TRPC3 Channels Transduce Mechanical Force And Accerelate Wound Contraction
Kenichiro Kawai, MD, PhD1; Hisako Ishise, MD1; Barrett Larson, MD2; Soh Nishimoto, MD, PhD1; Toshihiro Fujiwara, MD, PhD1; Masao Kakibuchi, MD, PhD1
1Hyogo College of Medicine, Nishinomiya, Japan, 2Stanford University, Stanford, CA
10:51 am 170. The Effect Of Bone Marrow Derived Stem Cell Induced By amD-3100 On Expanded Flap
Hii-Sun Jeong, MD, PhD1; Hye-Kyung Lee, MD, PhD2; Kwan-Chul Tark, MD, PhD3; Dae-Hyun Lew, MD, PhD3; In Suck Suh, MD, PhD1
1Kangnam Sacred Heart Hospital, Hallym University Medical Center, Hallym University College of Medicine, Seoul, Korea, Republic of, 2Department of Plastic and Reconstructive Surgery, Eulji General Hospital, Eulji University School of Medicine, Seoul, Korea, Republic of, 3Department of Plastic and Reconstructive Surgery, Yonsei University College of Medicine, Seoul, Korea, Republic of
10:58 am 171. Rational Identification of Novel Surface Markers to Enhance Cell Therapies
Michael Januszyk, MD; Robbert C. Rennert, MD; Michael Sorkin, MD; Melanie Rodrigues, PhD; Dominik Duscher, MD; Michael T. Chung, MD; Kevin Paik, BS; Revanth Kosaraju, BS; Michael Findlay, MD, PhD; Jason P. Glotzbach, MD, PhD; Zeshaan N. Maan, MBBS, MRCS; Atul J. Butte, MD, PhD; Geoffrey C. Gurtner, MD, PhD
Stanford University, Stanford, CA
11:05 am 172. Detection of Novel Cancer Subpopulations Through Integration of Public Microarray Data with Single Cell Gene Expression Profiling
Michael Januszyk, MD; Nadine Jahchan, PhD; Purvesh Khatri, PhD; Robbert C. Rennert, MD; Michael Sorkin, MD; Julien Sage, PhD; Michael T. Longaker, MD; Atul J. Butte, MD, PhD; Geoffrey C. Gurtner, MD
Stanford University, Stanford, CA
11:12 am 173. The Cellular and Molecular Dynamics of Burn Injury Progression Following Partial Thickness Burns: The Effect of Early and Late Debridement
Ian Chow, BA, Wei Xu, PhD; Solmaz N. Niknam-Bienia, MD, MHA; Shengxian Jia, MD; Ping Xie, MD, PhD; Sumanas W. Jordan, MD, PhD; Seok J. Hong, PhD; Thomas A. Mustoe, MD; Robert D. Galiano, MD
Northwestern University, Chicago, IL
11:19 am 174. TRPC3 Channels Regulate Expression of Fibronectin Via NF?B Signling in Response to Cyclic Strain And Contribute to Hypertrophic Scar Formation
Kenichiro Kawai, MD, PhD1; Hisako Ishise, MD1; Barrett Larson, MD2; Soh Nishimoto, MD, PhD1; Toshihiro Fujiwara, MD, PhD1; Masao Kakibuchi, MD, PhD1
1Hyogo College of Medicine, Nishinomiya, Japan, 2Stanford University, Stanford, CA
11:26 am 175. The Role of Fibronectin on Spatial Organization in 3D Culture: a Model for Wound Healing after Breast Reconstruction and Post-Mastectomy Radiation Therapy
Henry C. Hsia, MD; Sibo Tian, BA; Sharad Goyal, MD; Bruce G. Haffty, MD; Ting Chen, PhD; Ramsey A. Foty, PhD
Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ
11:33 am 176. Single Cell Transcriptomic Analysis of Human Fetal Bone Marrow-Derived Mesenchymal Stem Cells in Wound Healing
Sacha M.L. Khong, PhD; Dominik Duscher, MD; Michael Januszyk, MD; Peter A. Than, MD; Zeshaan Maan, MD; Geoffrey C. Gurtner, MD
Stanford University, Stanford, CA
11:40 am 177. Angiotensin Receptor Blockade is Associated with Decreased Cutaneous Scar Formation in a Rat Model: A Preclinical Study
Amanda M. Murphy, MD; Michael Bezuhly, MD, MSc, SM, FRCSC; Simon Gebremeskel, BSc; Terry LeVatte, BA; Paul Gratzer, PhD
Dalhousie University, Halifax, NS, Canada
11:47 am 178. Activation of Hif by Small Molecule Inhibitors of Phd2 Accelerates Wound Healing In Vivo
Michael Hu, MD, MPH, MS1; Wan Xing Hong, MS1; Min Xie, PhD2; Shibing Tang, PhD2; Robert Rennert, MD1; Graham Walmsley, BS1; Zeshaan Maan, MD1; Andrew Zimmermann, BS1; Geoffrey Gurtner, MD1; Amato Giaccia, PhD1; Peter Lorenz, MD1; Sheng Ding, PhD1; Michael Longaker, MD, MBA1
1Stanford, Stanford, CA, 2UCSF, San Francisco, CA
12:00 - 12:30 pm Awards Announcements & Adjourn
Cascade Ballroom